: "Breakpoints" (susceptible, intermediate, or resistant) tailored to the unique growth characteristics of these bacteria.
The document, titled Methods for Antimicrobial Dilution and Disk Susceptibility Testing of Infrequently Isolated or Fastidious Bacteria , is a specialized guideline developed by the Clinical and Laboratory Standards Institute (CLSI) . It serves as a critical extension to the primary antimicrobial susceptibility testing (AST) standards, specifically covering organisms that are not included in the more common CLSI M100 supplement. Core Purpose and Scope clsi document m45 pdf
: Abiotrophia and Granulicatella species (nutritionally variant streptococci), Aeromonas species, Pasteurella species, and the HACEK group (e.g., Aggregatibacter , Cardiobacterium ). Core Purpose and Scope : Abiotrophia and Granulicatella
: Tentative guidance for certain potential agents, as seen in the CLSI AST Newsletter . Current Edition and Availability Organisms Covered in CLSI M45
: Specialized advice on drug selection, incubation environments (e.g., increased CO2cap C cap O sub 2 ), and quality control (QC) procedures. Organisms Covered in CLSI M45