!!exclusive!! — Sakitamiwa Classification

The edema at the ulcer margin begins to subside, and the ulcer base appears cleaner. The white coating may begin to thin. 2. Healing Stage (H1 & H2)

This classification is a critical tool in clinical trials to evaluate the efficacy of acid-suppressing drugs like Proton Pump Inhibitors (PPIs) and Potassium-Competitive Acid Blockers (P-CABs) .

The ulcer is deep with a thick, white or yellowish-gray coating (slough) at the base. The margins are sharp and often swollen with edema. sakitamiwa classification

In modern research, doctors often assign numerical scores to these stages to quantitatively measure improvement. For example, a study on ischemic colitis or Behçet’s disease might use the following scale: Clinical Meaning Numerical Score (Example) Highly Active / Deep A2 Active / Slightly Improved H1 Early Healing H2 Advanced Healing S1 Red Scar (Healed) S2 White Scar (Mature) Why is this Classification Important?

The ulcer becomes shallower as granulation tissue fills the base. Regenerating epithelium (new skin) begins to creep in from the edges, often creating a "palisade" appearance of mucosal folds. The edema at the ulcer margin begins to

The ulcer is significantly smaller. The regenerating epithelium covers most of the base, leaving only a tiny central defect. 3. Scarring Stage (S1 & S2)

This transition indicates that medical treatment or natural recovery is effectively closing the wound. Healing Stage (H1 & H2) This classification is

At this point, the ulcer is considered "endoscopically cured" because the mucosal defect has vanished.